Research lines

Line 1: Development of Biotechnology for Industrial Processes and Environmental Protection

Description: Development of processes for transforming biomolecules and producing biomolecules of high added value with GMOs or enzymes obtained by recombinant DNA techniques, as well as bioprocesses aimed at environmental protection will be investigated.

Ana Teresa Lombardi
Anderson Ferreira da Cunha
Clovis Wesley Oliveira de Souza
Paulo Teixeira Lacava

Line 2: Development of Biotechnological Products

Description: Studies aimed at identification, expression, and purification of biomolecules; design of equipment and instrumentation for analysis; as well as the development of biotechnology services, such as disease diagnostic devices, gene expression analysis.

Bruno Campos Janegitz
Cristiane Sanchez Farinas
Moacir Rossi Forim
Odílio Benedito Garrido de Assis
Flavio Henrique Silva
Debora Marcondes Bastos Pereira Milori

Line 3: Biotechnology in Silico

Description: Aims at the use of computational methods to understand the structure of biological molecules and biomolecular complexes, involving information mining and management, virtual screening to search for molecules with biological activity, determination of reaction mechanisms, selection of targets for compounds, recognition of binding sites, study of interactions that determine the binding mode and modeling of experimental data, to allow time, cost and risk reduction in development processes and/or and increase in the effectiveness of drugs, pesticides, and other biotechnological products. Among the techniques used are computer simulation using molecular docking, molecular dynamics, molecular interaction calculations, and determination of structures by X-ray diffraction of small molecules.

Ignez Caracelli
Julio Zukerman Schpector
Paulino Ribeiro Villas Boas

Line 4: Nanobiotechnology

Description: Area focused on combining biotechnology with nanotechnology, which aims to investigate the interaction of active molecules and diverse nanostructured systems such as nanoparticles, nanofibers, nanomembranes, nanostructured films, etc., for the production of electronic, magnetic, biotechnological systems and devices. aspects related to the interaction of biomolecules and biomolecular assemblies with electronic structures or materials, aiming at applications in the areas of biology, biochemistry, and medicine.

Daniel Souza Correa
Henriette Monteiro Cordeiro de Azeredo
Fernando Manuel Araujo Moreira

Line 5: Biotechnological Applications in Medicine

Description: Due to the great advances that have been achieved with Biotechnology in the knowledge of the causes of many diseases, modern society needs to prepare itself to manage, share and regulate the opportunities, challenges, and risks of new technologies. State-of-the-art techniques have been used, such as photodynamic therapy in cancer and microbiological control; toxicity study of new materials in vitro and in vivo; bioprospecting of natural compounds against parasitic and infectious diseases; the release of inflammatory mediators, among others.

Angela Merice de Oliveira Leal
Meliza Goi Roscani
Cristina Paiva de Sousa
Euclides Matheucci Jr
Fernanda de Freitas Anibal
Aparecida Maria Catai
Vanderlei Salvador Bagnato